Bacterial DNA gyrase is a type II topoisomerase that can introduce negative supercoils to DNA substrates and is a clinically-relevant target for the development of new antibacterials.DNA gyrase is one of the primary targets of quinolones, broad-spectrum antibacterial agents and are used as a first-line drug for various types of infections.However,
Dissonance-based Program for Eating Disorders Prevention in Mexican University Students
The purpose of this study was to identify changes in the risk of eating disorders after a one-year follow-up of a dissonance-based eating disorders prevention program.The Body Billiard Tables Project was implemented in a sample of male and female university students: 133, 110, and 74 at baseline, post-test, and follow-up respectively, and we tested
Benchmarking of Document Image Analysis Tasks for Palm Leaf Manuscripts from Southeast Asia
This paper presents a comprehensive test of the principal tasks in document image analysis (DIA), starting with binarization, text line segmentation, and isolated character/glyph recognition, and continuing on to word recognition and transliteration for a new and challenging collection of palm leaf manuscripts from Southeast Asia.This research pres
TRPM8 Channels and Dry Eye
Transient receptor potential (TRP) Party channels transduce signals of chemical irritation and temperature change from the ocular surface to the brain.Dry eye disease (DED) is a multifactorial disorder wherein the eyes react to trivial stimuli with abnormal sensations, such as dryness, blurring, presence of foreign body, discomfort, irritation, and